6-(4-Bromophenyl)-2-ethoxy-4-(4-ethoxyphenyl)nicotinonitrile
نویسندگان
چکیده
The mol-ecule of the title nicotinonitrile derivative, C(22)H(19)BrN(2)O(2), is non-planar, the central pyridine ring making dihedral angles of 7.34 (14) and 43.56 (15)° with the 4-bromo-phenyl and 4-ethoxy-phenyl rings, respectively. The eth-oxy group of the 4-ethoxy-phenyl is slightly twisted from the attached benzene ring [C-O-C-C = 174.2 (3)°], whereas the eth-oxy group attached to the pyridine ring is in a (+)syn-clinal conformation [C-O-C-C = 83.0 (3)°]. A weak intra-molecular C-H⋯N inter-action generates an S(5) ring motif. In the crystal structure, the mol-ecules are linked by weak inter-molecular C-H⋯N inter-actions into screw chains along the b axis. These chains stacked along the a axis. π-π inter-actions with centroid-centroid distances of 3.8724 (16) and 3.8727 (16) Å are also observed.
منابع مشابه
6-(4-Bromophenyl)-2-ethoxy-4-(2,4,6-trimethoxyphenyl)nicotinonitrile1
In the asymmetric unit of the title nicotinonitrile derivative, C(23)H(21)BrN(2)O(4), there are two non-planar independent mol-ecules. The central pyridine ring makes dihedral angles of 9.05 (7) and 77.06 (7)°, respectively, with the 4-bromo-phenyl and 2,4,6-trimethoxy-phenyl rings in one mol-ecule, whereas the corresponding values are 5.96 (7) and 82.37 (7)° in the other. All the three meth-ox...
متن کامل6-(4-Aminophenyl)-2-ethoxy-4-(2-thienyl)nicotinonitrile
In the title nicotinonitrile derivative, C(18)H(15)N(3)OS, the central pyridyl ring makes dihedral angles of 25.22 (10) and 24.80 (16)° with the 4-amino-phenyl and thio-phene rings, respectively. The thio-phene ring is disordered over two orientations by rotation around the C(thio-phene)-C(pyridine) bond; the occupancies are 0.858 (2) and 0.142 (2). The eth-oxy group is slightly twisted from th...
متن کاملEthyl 4-(4-bromophenyl)-6-(4-ethoxyphenyl)-2-oxocyclohex-3-enecarboxylate
The title compound, C(23)H(23)BrO(4), is an inter-mediate in the synthesis of fused heterocycles. In the title mol-ecule, the cyclo-hexene ring has a distorted half-chair conformation. The bromo-phenyl ring and the mean plane of the cyclo-hexene ring form a dihedral angle of 13.8 (3)°, whereas the benzene and cyclo-hexene rings are approximately perpendicular [88.44 (17)°]. There are only weak ...
متن کامل(E)-1-{4-[Bis(4-bromophenyl)methyl]piperazin-1-yl}-3-(4-ethoxy-3-methoxyphenyl)prop-2-en-1-one
In the title mol-ecule, C(29)H(30)Br(2)N(2)O(3), the piperazine ring has a chair conformation and the C=C double bond has an E conformation. The dihedral angle between the bromo-benzene rings is 79.1 (3)°. In the crystal, mol-ecules are linked through C-H⋯O and C-H⋯Br hydrogen bonds.
متن کامل(E)-2-Ethoxy-6-[(4-ethoxyphenyl)iminomethyl]phenol
In the asymmetric unit of the title compound, C(17)H(19)NO(3), there are three independent mol-ecules, which are align nearly parallel to each other and adopt the phenol-imine tautomeric form. In each mol-ecule, an intra-molecular O-H⋯N hydrogen bond results in the formation of an S(6) ring motif. The dihedral angles between the aromatic rings in the three independent mol-ecules are 13.55 (2), ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2009